INT301217

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.78
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
granulocytes 1
Mir29a (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myeloid Leukemia 56 96.38 Very High Very High Very High
Myelodysplastic Syndromes 1 88.32 High High
Myeloproliferative Disorder 22 87.12 High High
Hematologic Neoplasms 2 85.28 High High
Disease 8 74.88 Quite High
Leukemia 17 54.96 Quite High
Malignant Neoplastic Disease 3 54.28 Quite High
Breast Cancer 2 50.72 Quite High
Lifespan 1 49.76 Quite Low
Targeted Disruption 2 41.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Self-renewal of AML stem cells and leukemic transformation has been previously linked to the lipid phosphatase PTEN (Yilmaz et al., 2006), which is predicted by some target prediction algorithms as a target of miR-29a (Lewis et al., 2005; Grimson et al., 2007); however, PTEN protein and mRNA were expressed at equivalent levels in WT and miR-29a┬ľoverexpressing Mac-1+ Gr-1+ granulocytes (unpublished data).
miR-29a Binding (target) of in granulocytes associated with myeloid leukemia
1) Confidence 0.08 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839143 Disease Relevance 0.78 Pain Relevance 0

General Comments

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