INT301241

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.85
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Runx1) DNA binding (Runx1) transcription factor binding (Runx1)
Mir29a (Mus musculus)
Runx1 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 3 5.00 Very Low Very Low Very Low
isoflurane 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myeloid Leukemia 168 100.00 Very High Very High Very High
Myeloproliferative Disorder 66 100.00 Very High Very High Very High
Disease 24 99.58 Very High Very High Very High
Malignant Neoplastic Disease 9 93.36 High High
Cancer 21 93.08 High High
Lifespan 3 88.84 High High
Disease Progression 3 82.88 Quite High
Leukemia 51 72.72 Quite High
Lymphatic System Cancer 3 67.44 Quite High
Targeted Disruption 6 64.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, overexpression of miR-29b or miR-29c does not recapitulate the phenotype of miR-29a overexpression, indicating that miR-29a uniquely induces an MPD and AML.
miR-29a Positive_regulation (induces) of AML associated with myeloproliferative disorder and myeloid leukemia
1) Confidence 0.00 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839143 Disease Relevance 0.99 Pain Relevance 0
The amount of time required to accumulate such additional genetic and/or epigenetic changes may account for the observed disease latency observed in miR-29a–induced AML.
miR-29a Positive_regulation (induced) of AML associated with myeloid leukemia and disease
2) Confidence 0.00 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839143 Disease Relevance 1.01 Pain Relevance 0
As miR-29a–induced AML exhibited serial transplantability, we sought to determine whether it also contained a definable LSC population.
miR-29a Positive_regulation (induced) of AML associated with myeloid leukemia
3) Confidence 0.00 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839143 Disease Relevance 0.84 Pain Relevance 0

General Comments

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