INT301243

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.66
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mvd) lyase activity (Mvd) peroxisome (Mvd)
kinase activity (Mvd)
Anatomy Link Frequency
myeloid cells 1
Mir29a (Mus musculus)
Mvd (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 2 5.00 Very Low Very Low Very Low
isoflurane 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myeloproliferative Disorder 44 100.00 Very High Very High Very High
Hematological Disease 12 99.96 Very High Very High Very High
Myeloid Leukemia 112 99.80 Very High Very High Very High
Cancer 14 93.08 High High
Hyperplasia 4 90.44 High High
Lymphatic System Cancer 2 66.80 Quite High
Splenomegaly 2 66.64 Quite High
Targeted Disruption 4 64.08 Quite High
Disease 16 28.56 Quite Low
Leukemia 34 26.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, overexpression of miR-29b or miR-29c does not recapitulate the phenotype of miR-29a overexpression, indicating that miR-29a uniquely induces an MPD and AML.
miR-29a Positive_regulation (induces) of MPD associated with myeloproliferative disorder and myeloid leukemia
1) Confidence 0.03 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839143 Disease Relevance 0.98 Pain Relevance 0
miR-29a–induced MPD may result from population expansion at the level of myeloid progenitors or proliferation of more mature myeloid cells.
miR-29a Positive_regulation (induced) of MPD in myeloid cells associated with myeloproliferative disorder
2) Confidence 0.03 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839143 Disease Relevance 0.68 Pain Relevance 0

General Comments

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