INT301265

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Context Info
Confidence 0.45
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.90
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Clec5a)
Clec5a (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 40 99.96 Very High Very High Very High
cytokine 14 92.56 High High
Arthritis 74 86.36 High High
rheumatoid arthritis 16 52.40 Quite High
Inflammation 72 50.00 Quite Low
antagonist 8 47.36 Quite Low
imagery 6 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 106 86.36 High High
Pressure And Volume Under Development 18 84.44 Quite High
Peripheral Arterial Disease 2 79.60 Quite High
Disease 44 61.20 Quite High
Rheumatoid Arthritis 16 52.40 Quite High
INFLAMMATION 60 50.00 Quite Low
Hypercalcemia 14 43.92 Quite Low
Arthropathy 10 5.00 Very Low Very Low Very Low
Dengue 6 5.00 Very Low Very Low Very Low
Osteoporosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mice were then treated s.c. with 0.5–1 mg of anti–MDL-1 or IgG1 isotype control.
Regulation (control) of MDL-1
1) Confidence 0.45 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839155 Disease Relevance 0.52 Pain Relevance 0.18
Importantly, genes associated with bone destruction such as RANKL, MMP9, ATPV0D2, and TRAP are down-regulated in paws after MDL-1–Ig fusion treatment and up-regulated in anti–MDL-1 agonist treatment.
Regulation (regulated) of MDL-1 associated with agonist
2) Confidence 0.45 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839155 Disease Relevance 0.38 Pain Relevance 0.29

General Comments

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