INT301283

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Nfatc1, Ctsk) peptidase activity (Ctsk) extracellular space (Ctsk)
nucleus (Nfatc1) DNA binding (Nfatc1) lysosome (Ctsk)
Anatomy Link Frequency
osteoclast 1
Nfatc1 (Mus musculus)
Ctsk (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 20 89.20 High High
Inflammation 36 51.68 Quite High
cytokine 7 41.16 Quite Low
Arthritis 37 31.16 Quite Low
rheumatoid arthritis 8 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 7 78.16 Quite High
Arthritis 53 62.44 Quite High
INFLAMMATION 30 50.00 Quite Low
Arthropathy 5 45.68 Quite Low
Pressure And Volume Under Development 9 33.04 Quite Low
Disease 22 5.48 Low Low
Rheumatoid Arthritis 8 5.00 Very Low Very Low Very Low
Dengue 3 5.00 Very Low Very Low Very Low
Osteoporosis 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TRAP and cathepsin K are osteoclast-specific genes regulated by the NFATc1 transcription factor (Matsumoto et al., 2004; Takayanagi, 2005a).
NFATc1 Regulation (regulated) of cathepsin K in osteoclast
1) Confidence 0.06 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839155 Disease Relevance 0.19 Pain Relevance 0.13

General Comments

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