INT301289

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.01
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Atp6v0d2) transport (Atp6v0d2) plasma membrane (Clec5a)
Anatomy Link Frequency
osteoclasts 3
Clec5a (Mus musculus)
Atp6v0d2 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 36 89.48 High High
Arthritis 37 88.28 High High
agonist 20 26.88 Quite Low
Pain 2 17.84 Low Low
rheumatoid arthritis 8 5.00 Very Low Very Low Very Low
cytokine 7 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 7 97.20 Very High Very High Very High
Pressure And Volume Under Development 9 95.08 Very High Very High Very High
INFLAMMATION 30 89.48 High High
Arthritis 53 88.28 High High
Bone Cancer 2 76.00 Quite High
Arthropathy 5 68.00 Quite High
Leukoencephalopathies 1 56.00 Quite High
Disease 22 52.24 Quite High
Bone Cysts 1 24.40 Low Low
Pain 1 17.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We also demonstrate that MDL-1 activation increases the expression of NFATc1 and ATPV0D2, which control cell fusion (Lee et al., 2006), as well as regulating bone resorption via TRAP and cathepsin K in osteoclasts (Takayanagi, 2005a).
Positive_regulation (activation) of MDL-1 in osteoclasts Positive_regulation (increases) of Gene_expression (expression) of ATPV0D2 in osteoclasts associated with hypercalcemia
1) Confidence 0.02 Published 2010 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2839155 Disease Relevance 1.01 Pain Relevance 0.28

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox