INT301307

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.42
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (LTC4S) small molecule metabolic process (LTC4S) lyase activity (LTC4S)
endoplasmic reticulum (LTC4S) signal transducer activity (GPR17) lipid binding (LTC4S)
GPR17 (Homo sapiens)
LTC4S (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 4 86.16 High High
agonist 16 77.60 Quite High
antagonist 12 17.48 Low Low
Hippocampus 12 5.00 Very Low Very Low Very Low
amygdala 6 5.00 Very Low Very Low Very Low
chemokine 6 5.00 Very Low Very Low Very Low
Dopamine 6 5.00 Very Low Very Low Very Low
Thalamus 6 5.00 Very Low Very Low Very Low
Cholecystokinin 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 6 98.12 Very High Very High Very High
Frailty 4 86.44 High High
Cv Unclassified Under Development 4 84.12 Quite High
Bordatella Infection 14 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 8 5.00 Very Low Very Low Very Low
Anaplastic Astrocytoma 4 5.00 Very Low Very Low Very Low
Appetite Loss 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Of note, no binding of LTC4 and LTD4 to GPR17 was seen in this study (Maekawa et al., 2009)
GPR17 Neg (no) Binding (binding) of LTC4
1) Confidence 0.00 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2839267 Disease Relevance 0.42 Pain Relevance 0.07
As shown in Figure S3, LTC4 did not activate or bind to hGPR17-L, -S or mGPR17, whereas this was readily observed for CysLT2.
hGPR17 Neg (not) Binding (bind) of LTC4
2) Confidence 0.00 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2839267 Disease Relevance 0 Pain Relevance 0.04

General Comments

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