INT30133

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Context Info
Confidence 0.27
First Reported 1988
Last Reported 1988
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 5
Disease Relevance 2.49
Pain Relevance 2.71

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extracellular region (Cck, Penk) extracellular space (Cck) DNA binding (Cck)
Anatomy Link Frequency
mossy fibers 5
Cck (Mus musculus)
Penk (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 10 100.00 Very High Very High Very High
Cholecystokinin 10 100.00 Very High Very High Very High
Enkephalin 25 99.74 Very High Very High Very High
Dynorphin 5 80.56 Quite High
Disease Link Frequency Relevance Heat
Epilepsy 15 95.04 Very High Very High Very High
Convulsion 15 90.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunocytochemical analyses of enkephalin-(ENK-I) and cholecystokinin-immunoreactivity (CCK-I) in contralateral hippocampus of animals sacrificed at various postlesion intervals revealed that both ENK-I and CCK-I were depleted from the mossy fibers at 6 and 12 hr postlesion, and that ENK-I rebounded to supranormal levels by 27 hr.
CCK-I Binding (rebounded) of ENK-I in mossy fibers associated with hippocampus, enkephalin and cholecystokinin
1) Confidence 0.27 Published 1988 Journal Peptides Section Abstract Doc Link 2856653 Disease Relevance 0.50 Pain Relevance 0.54
Immunocytochemical analyses of enkephalin-(ENK-I) and cholecystokinin-immunoreactivity (CCK-I) in contralateral hippocampus of animals sacrificed at various postlesion intervals revealed that both ENK-I and CCK-I were depleted from the mossy fibers at 6 and 12 hr postlesion, and that ENK-I rebounded to supranormal levels by 27 hr.
CCK-I Binding (rebounded) of ENK-I in mossy fibers associated with hippocampus, enkephalin and cholecystokinin
2) Confidence 0.27 Published 1988 Journal Peptides Section Abstract Doc Link 2856653 Disease Relevance 0.48 Pain Relevance 0.53
Immunocytochemical analyses of enkephalin-(ENK-I) and cholecystokinin-immunoreactivity (CCK-I) in contralateral hippocampus of animals sacrificed at various postlesion intervals revealed that both ENK-I and CCK-I were depleted from the mossy fibers at 6 and 12 hr postlesion, and that ENK-I rebounded to supranormal levels by 27 hr.
cholecystokinin Binding (rebounded) of ENK-I in mossy fibers associated with hippocampus, enkephalin and cholecystokinin
3) Confidence 0.27 Published 1988 Journal Peptides Section Abstract Doc Link 2856653 Disease Relevance 0.50 Pain Relevance 0.55
Immunocytochemical analyses of enkephalin-(ENK-I) and cholecystokinin-immunoreactivity (CCK-I) in contralateral hippocampus of animals sacrificed at various postlesion intervals revealed that both ENK-I and CCK-I were depleted from the mossy fibers at 6 and 12 hr postlesion, and that ENK-I rebounded to supranormal levels by 27 hr.
cholecystokinin Binding (rebounded) of ENK-I in mossy fibers associated with hippocampus, enkephalin and cholecystokinin
4) Confidence 0.27 Published 1988 Journal Peptides Section Abstract Doc Link 2856653 Disease Relevance 0.50 Pain Relevance 0.55
Immunocytochemical analyses of enkephalin-(ENK-I) and cholecystokinin-immunoreactivity (CCK-I) in contralateral hippocampus of animals sacrificed at various postlesion intervals revealed that both ENK-I and CCK-I were depleted from the mossy fibers at 6 and 12 hr postlesion, and that ENK-I rebounded to supranormal levels by 27 hr.
CCK-I Binding (rebounded) of ENK-I in mossy fibers associated with hippocampus, enkephalin and cholecystokinin
5) Confidence 0.27 Published 1988 Journal Peptides Section Abstract Doc Link 2856653 Disease Relevance 0.50 Pain Relevance 0.54

General Comments

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