INT301366

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Context Info
Confidence 0.04
First Reported 2004
Last Reported 2004
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Fgfr3) signal transduction (Fgf18) extracellular region (Fgf18)
nucleolus (Fgf18) nucleus (Fgfr3) kinase activity (Fgfr3)
Anatomy Link Frequency
chondrocyte 1
Fgf18 (Mus musculus)
Fgfr3 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 3 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 1 85.20 High High
Sarcoma 4 79.60 Quite High
Osteochondroma 40 73.84 Quite High
Cancer 13 50.08 Quite High
Multiple Hereditary Exostoses 45 50.00 Quite Low
Congenital Anomalies 5 22.40 Low Low
Osteoarthritis 3 6.76 Low Low
Chondrosarcoma 19 5.00 Very Low Very Low Very Low
Malignant Neoplastic Disease 17 5.00 Very Low Very Low Very Low
Syndrome 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, activation of FGFR3 in the proliferative zone (Fig. 5), by FGF18 [84] inhibits chondrocyte proliferation via phosphorylation of STAT-1 and subsequent upregulation of p21WAF/CIP1, which can inhibit the cell cycle [85].
FGF18 Positive_regulation (activation) of FGFR3 in chondrocyte
1) Confidence 0.04 Published 2004 Journal Hered Cancer Clin Pract Section Body Doc Link PMC2840003 Disease Relevance 0.34 Pain Relevance 0

General Comments

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