INT301409

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lpar6, Gpr87) plasma membrane (Lpar6, Gpr87) signal transducer activity (Lpar6, Gpr87)
molecular_function (Lpar6) biological_process (Lpar6)
Lpar6 (Mus musculus)
Gpr87 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 16 5.00 Very Low Very Low Very Low
agonist 15 5.00 Very Low Very Low Very Low
Neuropathic pain 9 5.00 Very Low Very Low Very Low
fibrosis 9 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Potency 5 5.00 Very Low Very Low Very Low
dorsal root ganglion 4 5.00 Very Low Very Low Very Low
metalloproteinase 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 92 50.00 Quite Low
Metastasis 67 50.00 Quite Low
Neuroblastoma 2 10.64 Low Low
Shock 1 6.16 Low Low
Breast Cancer 49 5.00 Very Low Very Low Very Low
Ovarian Cancer 19 5.00 Very Low Very Low Very Low
Targeted Disruption 19 5.00 Very Low Very Low Very Low
Apoptosis 15 5.00 Very Low Very Low Very Low
Neuropathic Pain 11 5.00 Very Low Very Low Very Low
Disease 8 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
for GPR87; P2Y5-F (5?
P2Y5 Binding (for) of GPR87
1) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2840030 Disease Relevance 0 Pain Relevance 0
Now that GPR87 has been shown independently to be activated by LPA (Wetter et al., 2009), it might qualify for the designation LPA6; consequently, P2Y5 would be LPA7, P2Y10 and GPR35, if confirmed, would be LPA8 and LPA9, respectively.
LPA6 Binding (activated) of GPR87
2) Confidence 0.06 Published 2010 Journal British Journal of Pharmacology Section Body Doc Link PMC2989581 Disease Relevance 0 Pain Relevance 0

General Comments

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