INT301444

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Carm1) methyltransferase activity (Carm1) nucleus (Carm1)
cytoplasm (Carm1)
Anatomy Link Frequency
hearts 1
Carm1 (Mus musculus)
Pain Link Frequency Relevance Heat
fibrosis 1 10.56 Low Low
imagery 6 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stroke 1 22.40 Low Low
Cardiovascular Disorder Under Development 1 10.56 Low Low
Necrosis 2 7.20 Low Low
Targeted Disruption 7 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Hypertrophy 2 5.00 Very Low Very Low Very Low
Embryonic Lethality 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low
Repression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As Abu-Farah and colleagues found histone methyltransferase activity to be essential for target gene upregulation [32], we also determined the extent of H3K4 as well as H3K36 methylation in neonatal Smyd2 cKO versus control hearts, as these histone modifications are generally believed to be associated with actively transcribed genes [30]–[31], [48]–[49].
Positive_regulation (upregulation) of histone methyltransferase in hearts
1) Confidence 0.04 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2840034 Disease Relevance 0 Pain Relevance 0

General Comments

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