INT301463

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Context Info
Confidence 0.54
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Smyd2, Smyd1) cytoplasm (Smyd2, Smyd1) cytosol (Smyd2)
methyltransferase activity (Smyd2) DNA binding (Smyd1)
Smyd2 (Mus musculus)
Smyd1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 6 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Embryonic Lethality 2 99.84 Very High Very High Very High
Targeted Disruption 7 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low
Hypertrophy 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low
Repression 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Dilated Cardiomyopathy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast to Smyd1 deficiency, loss of Smyd2 does not result in embryonic lethality, consistent with implications from expression data that Smyd2 functions later in development.
Negative_regulation (loss) of Smyd2 Neg (not) Positive_regulation (result) of Gene_expression (deficiency) of Smyd1 associated with embryonic lethality
1) Confidence 0.54 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2840034 Disease Relevance 0.10 Pain Relevance 0

General Comments

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