INT301477

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Context Info
Confidence 0.33
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.31
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Smyd2, Sin3a, Smyd2) cytoplasm (Smyd2, Smyd2) cytosol (Smyd2, Smyd2)
methyltransferase activity (Smyd2, Smyd2) aging (Sin3a) DNA binding (Sin3a)
Smyd2 (Mus musculus)
Sin3a (Mus musculus)
Smyd2 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 6 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 1 99.96 Very High Very High Very High
Embryonic Lethality 2 74.96 Quite High
Targeted Disruption 7 72.76 Quite High
Cancer 2 61.04 Quite High
Stress 3 5.00 Very Low Very Low Very Low
Hypertrophy 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Dilated Cardiomyopathy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our in vitro studies, however, revealed that Smyd2 acts as a transcriptional repressor when bound to HDAC1 and the Sin3 repression complex [20].
Smyd2 Negative_regulation (repressor) of Sin3 Binding (bound) of Smyd2 associated with repression
1) Confidence 0.33 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2840034 Disease Relevance 0.31 Pain Relevance 0

General Comments

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