INT301496

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.69
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PPA1) small molecule metabolic process (CYP4F3) endoplasmic reticulum (CYP4F3)
cytoplasm (PPA1)
PPA1 (Homo sapiens)
CYP4F3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 16 92.44 High High
fibrosis 11 5.00 Very Low Very Low Very Low
agonist 11 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Bile 5 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Kinase C 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
fluoxetine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 15 92.44 High High
Fatty Liver 63 91.28 High High
Injury 8 87.08 High High
Obesity 11 79.68 Quite High
Hyperglycemia 3 78.48 Quite High
Liver Disease 18 77.44 Quite High
Metabolic Syndrome 23 70.00 Quite High
Stress 12 7.40 Low Low
Nash(non-alcoholic Steatohepatitis) 27 5.00 Very Low Very Low Very Low
Insulin Resistance 25 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
activation, the CYP4F genes were reported to be repressed during fasting and by peroxisome proliferators possibly by PP-CoA or PUFA-CoA mediated inhibition of HNF4?
PP Negative_regulation (repressed) of CYP4F
1) Confidence 0.01 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0.69 Pain Relevance 0.05

General Comments

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