INT301535

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Context Info
Confidence 0.14
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.46
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc27a4) endoplasmic reticulum (Slc27a4) plasma membrane (Slc27a4)
ligase activity (Slc27a4) lipid metabolic process (Slc27a4)
Slc27a4 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 32 5.00 Very Low Very Low Very Low
fibrosis 22 5.00 Very Low Very Low Very Low
agonist 22 5.00 Very Low Very Low Very Low
alcohol 10 5.00 Very Low Very Low Very Low
Bile 10 5.00 Very Low Very Low Very Low
chemokine 8 5.00 Very Low Very Low Very Low
Kinase C 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
fluoxetine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 22 100.00 Very High Very High Very High
Targeted Disruption 14 66.32 Quite High
Insulin Resistance 50 63.84 Quite High
Repression 4 32.20 Quite Low
Metabolic Syndrome 46 14.40 Low Low
Fatty Liver 126 5.00 Very Low Very Low Very Low
Nash(non-alcoholic Steatohepatitis) 54 5.00 Very Low Very Low Very Low
Liver Disease 36 5.00 Very Low Very Low Very Low
Diabetes Mellitus 34 5.00 Very Low Very Low Very Low
INFLAMMATION 30 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, the upregulated FATP2, FATP4 and FATP5 expression in obese rats increases TAG synthesis and storage, while increased FATP expression promotes the cellular importation of FFAs [33, 47], leading to FFA overload and hepatic steatosis.
Positive_regulation (increases) of Gene_expression (expression) of FATP4 associated with obesity
1) Confidence 0.14 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0.23 Pain Relevance 0
Therefore, the upregulated FATP2, FATP4 and FATP5 expression in obese rats increases TAG synthesis and storage, while increased FATP expression promotes the cellular importation of FFAs [33, 47], leading to FFA overload and hepatic steatosis.
Positive_regulation (upregulated) of Gene_expression (expression) of FATP4 associated with obesity
2) Confidence 0.14 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0.23 Pain Relevance 0

General Comments

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