INT301598

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Context Info
Confidence 0.41
First Reported 2009
Last Reported 2009
Negated 3
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.36
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (CYP4F2) endoplasmic reticulum (CYP4F2)
Anatomy Link Frequency
liver 1
skin 1
kidney 1
CYP4F2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 48 64.72 Quite High
Inflammatory response 3 47.20 Quite Low
alcohol 15 31.44 Quite Low
fibrosis 33 5.00 Very Low Very Low Very Low
agonist 33 5.00 Very Low Very Low Very Low
Bile 15 5.00 Very Low Very Low Very Low
chemokine 12 5.00 Very Low Very Low Very Low
Kinase C 9 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
methotrexate 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 45 64.72 Quite High
Starvation 24 45.32 Quite Low
Toxicity 15 12.32 Low Low
Fatty Liver 189 5.00 Very Low Very Low Very Low
Nash(non-alcoholic Steatohepatitis) 81 5.00 Very Low Very Low Very Low
Insulin Resistance 75 5.00 Very Low Very Low Very Low
Metabolic Syndrome 69 5.00 Very Low Very Low Very Low
Liver Disease 54 5.00 Very Low Very Low Very Low
Diabetes Mellitus 51 5.00 Very Low Very Low Very Low
Disease 39 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The human CYP4F P450s metabolize and inactivate the proinflammatory leukotriene B4 (LTB4) [118], with the myeloid-expressed CYP4F3A having a twofold greater affinity for LTB4 than CYP4F2 expressed in liver, kidney, and skin, but not in myeloid cells.
Neg (not) Gene_expression (expressed) of CYP4F2 in skin
1) Confidence 0.41 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0.12 Pain Relevance 0.06
The human CYP4F P450s metabolize and inactivate the proinflammatory leukotriene B4 (LTB4) [118], with the myeloid-expressed CYP4F3A having a twofold greater affinity for LTB4 than CYP4F2 expressed in liver, kidney, and skin, but not in myeloid cells.
Neg (not) Gene_expression (expressed) of CYP4F2 in liver
2) Confidence 0.14 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0.12 Pain Relevance 0.06
The human CYP4F P450s metabolize and inactivate the proinflammatory leukotriene B4 (LTB4) [118], with the myeloid-expressed CYP4F3A having a twofold greater affinity for LTB4 than CYP4F2 expressed in liver, kidney, and skin, but not in myeloid cells.
Neg (not) Gene_expression (expressed) of CYP4F2 in kidney
3) Confidence 0.14 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0.12 Pain Relevance 0.06

General Comments

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