INT301611

Context Info Confidence 0.21 First Reported 2009 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.15 Pain Relevance 0

small molecule metabolic process (CYP4F3) endoplasmic reticulum (CYP4F3)

CYP4F3 (Homo sapiens)

Pain Link Frequency Relevance Heat Kinase C 3 39.92 Inflammation 16 33.60 fibrosis 11 5.00 agonist 11 5.00 alcohol 5 5.00 Bile 5 5.00 chemokine 4 5.00 cytokine 2 5.00 methotrexate 1 5.00 fluoxetine 1 5.00

Disease Link Frequency Relevance Heat Repression 2 77.56 Obesity 11 69.44 Insulin Resistance 25 46.16 INFLAMMATION 15 33.60 Diabetes Mellitus 17 9.28 Liver Disease 18 8.88 Syndrome 2 7.84 Adrenoleukodystrophy 2 6.96 Disease 13 6.08 Fatty Liver 63 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

It is also possible that MCFAs and VLCFAs metabolized by the CYP4A and CYP4F may produce fatty acid metabolites that reciprocally regulate the expression of the CYP4A and CYP4F genes (Figure 1).

Regulation (regulate) of Gene_expression (expression) of CYP4F

1) Confidence 0.21 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0.15 Pain Relevance 0

General Comments

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