INT301627

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Context Info
Confidence 0.21
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.49
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Fabp1, Ppara) nucleus (Fabp1, Ppara) cytosol (Fabp1)
transport (Fabp1) DNA binding (Ppara) lipid metabolic process (Ppara)
Anatomy Link Frequency
nucleus 2
Fabp1 (Mus musculus)
Ppara (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 32 73.96 Quite High
fibrosis 22 5.00 Very Low Very Low Very Low
agonist 22 5.00 Very Low Very Low Very Low
alcohol 10 5.00 Very Low Very Low Very Low
Bile 10 5.00 Very Low Very Low Very Low
chemokine 8 5.00 Very Low Very Low Very Low
Kinase C 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
methotrexate 2 5.00 Very Low Very Low Very Low
fluoxetine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 30 73.96 Quite High
Diabetes Mellitus 34 73.24 Quite High
Liver Disease 36 72.84 Quite High
Syndrome 4 71.80 Quite High
Adrenoleukodystrophy 4 70.92 Quite High
Disease 26 70.04 Quite High
Targeted Disruption 14 30.96 Quite Low
Disease Progression 6 30.40 Quite Low
Repression 4 26.64 Quite Low
Fatty Liver 126 25.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recent studies have shown that L-FABP also functions to shuttle lipids to the nucleus to allow them to directly interact with PPAR?
L-FABP Binding (interact) of PPAR in nucleus
1) Confidence 0.21 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0 Pain Relevance 0
The mechanism of LCFA uptake and importation into the nucleus has recently been shown to be mediated by L-FABP, which binds polyunsaturated LCFAs with a greater affinity than saturated LCFAs and associates with PPAR?
L-FABP Binding (associates) of PPAR in nucleus
2) Confidence 0.15 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0.49 Pain Relevance 0.04

General Comments

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