INT301640

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) mitochondrion (Cyp2e1) endoplasmic reticulum (Cyp2e1)
enzyme binding (Cyp2e1) cell proliferation (Ros1) signal transduction (Ros1)
Cyp2e1 (Mus musculus)
Ros1 (Mus musculus)
Pain Link Frequency Relevance Heat
alcohol 5 19.44 Low Low
Inflammation 16 5.00 Very Low Very Low Very Low
fibrosis 11 5.00 Very Low Very Low Very Low
agonist 11 5.00 Very Low Very Low Very Low
Bile 5 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Kinase C 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
fluoxetine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 8 88.12 High High
Hepatotoxicity 1 84.08 Quite High
Fatty Liver 63 80.32 Quite High
Targeted Disruption 7 17.64 Low Low
Liver Disease 18 9.68 Low Low
Obesity 11 7.36 Low Low
Nash(non-alcoholic Steatohepatitis) 27 5.00 Very Low Very Low Very Low
Insulin Resistance 25 5.00 Very Low Very Low Very Low
Metabolic Syndrome 23 5.00 Very Low Very Low Very Low
Diabetes Mellitus 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The induction of CYP2E1 by many potentially toxic/carcinogenic substrates such as ethanol, benzene, and haloalkanes and their metabolisms promote ROS production [6].
Positive_regulation (induction) of CYP2E1 Positive_regulation (promote) of Gene_expression (production) of ROS
1) Confidence 0.03 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0.25 Pain Relevance 0

General Comments

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