INT301653

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Context Info
Confidence 0.08
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Scd1) endoplasmic reticulum (Scd1) nucleus (Mlxipl)
DNA binding (Mlxipl) transcription factor binding (Mlxipl) lipid metabolic process (Scd1)
Mlxipl (Mus musculus)
Scd1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 11 52.08 Quite High
antagonist 1 51.12 Quite High
Inflammation 16 5.00 Very Low Very Low Very Low
fibrosis 11 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Bile 5 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Kinase C 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperinsulinism 3 92.56 High High
Insulin Resistance 25 88.64 High High
Hyperglycemia 3 83.04 Quite High
Diabetes Mellitus 17 79.52 Quite High
Stress 12 31.96 Quite Low
Fatty Liver 63 26.96 Quite Low
Liver Disease 18 21.28 Low Low
Nash(non-alcoholic Steatohepatitis) 27 5.00 Very Low Very Low Very Low
Metabolic Syndrome 23 5.00 Very Low Very Low Very Low
INFLAMMATION 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
ChREBP has also been shown to increase the expression of many of the fatty acid synthesis enzymes as well as SCD-1, thereby facilitating the conversion of glucose to fatty acids.
ChREBP Positive_regulation (increase) of Gene_expression (expression) of SCD-1
1) Confidence 0.08 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0.50 Pain Relevance 0.05

General Comments

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