INT301658

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc27a4) endoplasmic reticulum (Slc27a4) carbohydrate metabolic process (Ins1)
ligase activity (Slc27a4) lipid metabolic process (Slc27a4) cytoplasm (Ins1)
Anatomy Link Frequency
hepatocytes 1
Ins1 (Mus musculus)
Slc27a4 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 11 85.52 High High
Bile 5 53.76 Quite High
Inflammation 16 5.00 Very Low Very Low Very Low
fibrosis 11 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Kinase C 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
fluoxetine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 11 99.10 Very High Very High Very High
Insulin Resistance 25 63.20 Quite High
Metabolic Syndrome 23 56.16 Quite High
Fatty Liver 63 56.00 Quite High
Targeted Disruption 7 39.76 Quite Low
Nash(non-alcoholic Steatohepatitis) 27 5.00 Very Low Very Low Very Low
Liver Disease 18 5.00 Very Low Very Low Very Low
Diabetes Mellitus 17 5.00 Very Low Very Low Very Low
INFLAMMATION 15 5.00 Very Low Very Low Very Low
Disease 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is therefore not surprising that FATP2 is induced in obese Zucker (fa/fa) rats and that both FATP2 and FATP4 mRNA are increased in hepatocytes by carbohydrates feeding and by insulin through SREBP-1c [35].
insulin Positive_regulation (increased) of FATP4 in hepatocytes associated with obesity
1) Confidence 0.01 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0.37 Pain Relevance 0.07

General Comments

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