INT30166

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.50
First Reported 1985
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 0.52
Pain Relevance 3.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Th) mitochondrion (Th) nucleus (Th)
response to stress (Th) cytoplasm (Th)
Anatomy Link Frequency
nucleus 4
ventricle 2
neurons 2
Th (Rattus norvegicus)
Th - S40Y (2)
Pain Link Frequency Relevance Heat
Morphine 38 100.00 Very High Very High Very High
withdrawal 28 100.00 Very High Very High Very High
addiction 3 100.00 Very High Very High Very High
narcan 12 93.16 High High
Catecholamine 2 81.20 Quite High
noradrenaline 4 80.28 Quite High
tetrodotoxin 1 71.92 Quite High
antagonist 1 67.36 Quite High
Disease Link Frequency Relevance Heat
Attention Deficit Hyperactivity Disorder 4 96.44 Very High Very High Very High
Ganglion Cysts 4 90.60 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Low-Na+ medium also increased the incorporation of 32Pi into tyrosine hydroxylase; the dependence of tyrosine hydroxylase phosphorylation on the Na+ concentration resembled that of DOPA synthesis.
Regulation (dependence) of Phosphorylation (phosphorylation) of tyrosine hydroxylase associated with addiction
1) Confidence 0.50 Published 1985 Journal J. Neurochem. Section Abstract Doc Link 2857766 Disease Relevance 0.25 Pain Relevance 0.16
The purpose of the present study was to evaluate the effects of morphine withdrawal on site-specific tyrosine hydroxylase (TH) phosphorylation in the rat left ventricle.
Regulation (effects) of Phosphorylation (phosphorylation) of TH in ventricle associated with withdrawal and morphine
2) Confidence 0.27 Published 2009 Journal Basic Res. Cardiol. Section Abstract Doc Link 19104749 Disease Relevance 0.10 Pain Relevance 0.97
The present findings demonstrate that the enhancement of total TH expression and the increase of the phosphorylation state of TH during morphine withdrawal are dependent on PKA and ERK and suggest that these transduction pathways might contribute to the activation of the cardiac catecholaminergic neurons in response to morphine- withdrawal.
Regulation (dependent) of Phosphorylation (phosphorylation) of TH in neurons associated with withdrawal and morphine
3) Confidence 0.24 Published 2009 Journal Basic Res. Cardiol. Section Abstract Doc Link 19104749 Disease Relevance 0 Pain Relevance 0.97
Regulation of serine (Ser)-31 and Ser40 tyrosine hydroxylase phosphorylation during morphine withdrawal in the hypothalamic paraventricular nucleus and nucleus tractus solitarius-A2 cell group: role of ERK1/2.
Regulation (Regulation) of Phosphorylation (phosphorylation) of tyrosine hydroxylase (S40Y) in nucleus associated with withdrawal and morphine
4) Confidence 0.05 Published 2007 Journal Endocrinology Section Title Doc Link 17823252 Disease Relevance 0.09 Pain Relevance 0.62
Regulation of serine (Ser)-31 and Ser40 tyrosine hydroxylase phosphorylation during morphine withdrawal in the hypothalamic paraventricular nucleus and nucleus tractus solitarius-A2 cell group: role of ERK1/2.
Regulation (Regulation) of Phosphorylation (phosphorylation) of tyrosine hydroxylase (S40Y) in nucleus associated with withdrawal and morphine
5) Confidence 0.02 Published 2007 Journal Endocrinology Section Title Doc Link 17823252 Disease Relevance 0.09 Pain Relevance 0.62

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox