INT301661

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Context Info
Confidence 0.02
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) cell proliferation (Ros1) signal transduction (Ros1)
small molecule metabolic process (CYP2B6) endoplasmic reticulum (CYP2B6) plasma membrane (Ros1)
Anatomy Link Frequency
hepatocytes 1
CYP2B6 (Homo sapiens)
Ros1 (Mus musculus)
Pain Link Frequency Relevance Heat
alcohol 5 89.04 High High
Inflammation 16 37.92 Quite Low
fibrosis 11 5.00 Very Low Very Low Very Low
agonist 11 5.00 Very Low Very Low Very Low
Bile 5 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Kinase C 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
fluoxetine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 8 92.48 High High
Liver Disease 18 79.28 Quite High
Obesity 11 76.96 Quite High
Fatty Liver 63 75.76 Quite High
Nash(non-alcoholic Steatohepatitis) 27 73.84 Quite High
Diabetes Mellitus 17 62.00 Quite High
Ketosis 1 61.28 Quite High
Hepatotoxicity 1 45.88 Quite Low
INFLAMMATION 15 37.92 Quite Low
Disease 13 36.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, the microsomal P450 monooxygenase system is a significant contributor of ROS formation in hepatocytes.


P450 Binding (formation) of ROS in hepatocytes
1) Confidence 0.02 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0.64 Pain Relevance 0.04

General Comments

This test has worked.

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