INT301663

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Context Info
Confidence 0.14
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ppara) small molecule metabolic process (CYP4A11) endoplasmic reticulum (CYP4A11)
nucleus (Ppara) DNA binding (Ppara) lipid metabolic process (Ppara)
Ppara (Mus musculus)
CYP4A11 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 11 99.84 Very High Very High Very High
Inflammation 16 33.40 Quite Low
fibrosis 11 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Bile 5 5.00 Very Low Very Low Very Low
chemokine 4 5.00 Very Low Very Low Very Low
Kinase C 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
methotrexate 1 5.00 Very Low Very Low Very Low
fluoxetine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fatty Liver 63 96.96 Very High Very High Very High
Nash(non-alcoholic Steatohepatitis) 27 96.24 Very High Very High Very High
Stress 12 93.52 High High
Hyperoxia 1 91.88 High High
Metabolic Syndrome 23 55.12 Quite High
Disease Progression 3 42.96 Quite Low
INFLAMMATION 15 33.40 Quite Low
Insulin Resistance 25 5.00 Very Low Very Low Very Low
Liver Disease 18 5.00 Very Low Very Low Very Low
Diabetes Mellitus 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast to the extensive data on the role of rodent CYP4A gene in animal models of steatosis and steatohepatitis, little is known about how the human CYP4A11 gene is controlled by PPAR?
PPAR Regulation (controlled) of CYP4A11
1) Confidence 0.14 Published 2009 Journal PPAR Research Section Body Doc Link PMC2840373 Disease Relevance 0.65 Pain Relevance 0.09

General Comments

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