INT301740

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Context Info
Confidence 0.44
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Dmd) cytoskeleton (Dmd) nucleus (Dmd)
cytoplasm (Dmd)
Anatomy Link Frequency
synapses 2
Dmd (Mus musculus)
Pain Link Frequency Relevance Heat
Neurotransmitter 22 98.52 Very High Very High Very High
Hippocampus 12 58.80 Quite High
Glutamate 3 36.88 Quite Low
GABAergic 8 18.08 Low Low
Central nervous system 8 5.00 Very Low Very Low Very Low
Glutamate receptor 6 5.00 Very Low Very Low Very Low
amygdala 5 5.00 Very Low Very Low Very Low
Kinase C 4 5.00 Very Low Very Low Very Low
Pyramidal cell 4 5.00 Very Low Very Low Very Low
sodium channel 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Helminth Infection 7 87.80 High High
Congenital Anomalies 12 60.84 Quite High
Cognitive Disorder 12 49.68 Quite Low
Muscular Dystrophy 46 5.00 Very Low Very Low Very Low
Targeted Disruption 15 5.00 Very Low Very Low Very Low
Intellectual Impairment 7 5.00 Very Low Very Low Very Low
Disease 5 5.00 Very Low Very Low Very Low
Apoptosis 4 5.00 Very Low Very Low Very Low
Frailty 3 5.00 Very Low Very Low Very Low
Lifespan 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus, it has been shown that the large dystrophin isoform DLP2 at the glutamatergic NMJ and the smaller Dp186 isoform at cholinergic central synapses, both postsynaptically localized, are required for wild-type levels of presynaptic neurotransmitter release.
Positive_regulation (required) of Localization (localized) of dystrophin in synapses associated with neurotransmitter
1) Confidence 0.44 Published 2009 Journal Mol Neurobiol Section Body Doc Link PMC2840664 Disease Relevance 0.15 Pain Relevance 0.14

General Comments

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