INT301931

Context Info Confidence 0.18 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 1.54 Pain Relevance 0

peptidase activity (PLAU) signal transduction (PLAU) extracellular space (PLAU) extracellular region (PLAU) plasma membrane (PLAU)

Anatomy Link Frequency HeLa 3 FaDu 1 PLAU (Homo sapiens)

Pain Link Frequency Relevance Heat COX-2 inhibitor 12 28.76 COX2 2 5.00 cytokine 2 5.00 cINOD 2 5.00 Inflammation 2 5.00

Disease Link Frequency Relevance Heat Cancer 124 95.44 Metastasis 26 79.28 Residual Neoplasm 4 67.12 Carcinoma 24 18.16 Malignant Neoplastic Disease 6 13.76 Skin Cancer 8 5.00 Recurrence 6 5.00 Reprotox - General 1 4 5.00 INFLAMMATION 4 5.00 Wound Healing 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Hence, the neo-angiogenic potential of FaDu and HeLa cells was strongly reduced upon inhibition of COX-2, MMPs, and the uPA-system.

Negative_regulation (reduced) of Negative_regulation (inhibition) of uPA in HeLa

1) Confidence 0.18 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2841144 Disease Relevance 0.77 Pain Relevance 0

Hence, the neo-angiogenic potential of FaDu and HeLa cells was strongly reduced upon inhibition of COX-2, MMPs, and the uPA-system.

Negative_regulation (reduced) of in FaDu Negative_regulation (inhibition) of uPA in HeLa

2) Confidence 0.06 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2841144 Disease Relevance 0.77 Pain Relevance 0

General Comments

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