INT301935

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.13
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 6
Disease Relevance 4.40
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (UCK2) small molecule metabolic process (UCK2) kinase activity (UCK2)
cellular_component (UCK2)
Anatomy Link Frequency
lower limb 2
FaDu 1
HeLa 1
UCK2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 8 98.88 Very High Very High Very High
Multiple sclerosis 20 96.60 Very High Very High Very High
peripheral neuropathy 16 77.56 Quite High
cINOD 4 11.84 Low Low
COX-2 inhibitor 24 5.00 Very Low Very Low Very Low
Migraine 8 5.00 Very Low Very Low Very Low
headache 6 5.00 Very Low Very Low Very Low
COX2 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Spasticity 14 100.00 Very High Very High Very High
INFLAMMATION 12 98.88 Very High Very High Very High
Cancer 248 98.44 Very High Very High Very High
Demyelinating Disease 24 96.60 Very High Very High Very High
Spastic Paraparesis 8 95.60 Very High Very High Very High
Metastasis 52 94.32 High High
Carcinoma 48 92.88 High High
Mitochondrial Disorders 8 85.44 High High
Chronic Progressive External Ophthalmoplegia 22 79.40 Quite High
Peripheral Neuropathy 16 77.56 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the two probands presenting with progressive lower limb spasticity (UK-3 and UK-5), no underlying metabolic, inflammatory or compressive causes were found despite extensive investigations over several years.
Gene_expression (presenting) of UK-5 in lower limb associated with spasticity and inflammation
1) Confidence 0.13 Published 2010 Journal Brain Section Body Doc Link PMC2842512 Disease Relevance 1.07 Pain Relevance 0.14
In the two probands presenting with progressive lower limb spasticity (UK-3 and UK-5), no underlying metabolic, inflammatory or compressive causes were found despite extensive investigations over several years.
Gene_expression (presenting) of UK-3 in lower limb associated with spasticity and inflammation
2) Confidence 0.13 Published 2010 Journal Brain Section Body Doc Link PMC2842512 Disease Relevance 1.07 Pain Relevance 0.14
FaDu and HeLa cells were treated with WX-UK1 alone or a combination of WX-UK1, Galardin®, and Celecoxib®, and plated on matrigel invasion chambers composed of 6-well inlays with 8 ?
Gene_expression (treated) of WX-UK1 in FaDu
3) Confidence 0.04 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2841144 Disease Relevance 0.41 Pain Relevance 0
The in vivo anti-metastatic and anti-proliferative activity of the synthetic uPA inhibitor WK-UK1 has been demonstrated in various animal tumour models.
Gene_expression (synthetic) of WK-UK1 associated with cancer
4) Confidence 0.04 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2841144 Disease Relevance 1.04 Pain Relevance 0
l medium (0.1% FCS) was added into inserts for 24 hours, as was WX-UK1 (Wilex, Munich, Germany) at a concentration of 1.0 ?
Gene_expression (added) of WX-UK1
5) Confidence 0.04 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2841144 Disease Relevance 0.40 Pain Relevance 0
FaDu and HeLa cells were treated with WX-UK1 alone or a combination of WX-UK1, Galardin®, and Celecoxib®, and plated on matrigel invasion chambers composed of 6-well inlays with 8 ?
Gene_expression (treated) of WX-UK1 in HeLa
6) Confidence 0.01 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2841144 Disease Relevance 0.41 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox