INT301954

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Context Info
Confidence 0.45
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.46
Pain Relevance 1.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tlr4) plasma membrane (Tlr4) intracellular (Tlr4)
cytoplasm (Tlr4)
Tlr4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Eae 37 99.84 Very High Very High Very High
allodynia 12 99.36 Very High Very High Very High
Inflammatory response 10 92.76 High High
Inflammation 26 90.08 High High
Neuropathic pain 18 88.84 High High
Thermal hyperalgesia 8 88.04 High High
cytokine 28 82.40 Quite High
intrathecal 6 81.76 Quite High
Pain 9 78.36 Quite High
chemokine 1 52.88 Quite High
Disease Link Frequency Relevance Heat
Injury 40 99.84 Very High Very High Very High
Neuropathic Pain 31 99.36 Very High Very High Very High
INFLAMMATION 36 92.36 High High
Hyperalgesia 10 88.04 High High
Repression 2 86.52 High High
Pain 12 78.36 Quite High
Pneumonia 1 68.48 Quite High
Nervous System Injury 3 56.20 Quite High
Adult Respiratory Distress Syndrome 2 51.60 Quite High
Lung Injury 13 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
during the CCI to demonstrate there has the same effect as TLR4 inhibition on CCI-induced allodynia should be verified in future.
Regulation (effect) of Negative_regulation (inhibition) of TLR4 associated with allodynia and eae
1) Confidence 0.45 Published 2010 Journal International Journal of Medical Sciences Section Body Doc Link PMC2920570 Disease Relevance 1.86 Pain Relevance 1.43
Second, we do not know whether inhibition of TLR4 with blocking antibodies affect the IRAK-3 response.
Spec (whether) Regulation (affect) of Spec (whether) Negative_regulation (inhibition) of TLR4
2) Confidence 0.40 Published 2010 Journal Respir Res Section Body Doc Link PMC2841148 Disease Relevance 0.59 Pain Relevance 0.35

General Comments

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