INT302119

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Oprm1, Ppp1r9b) cell differentiation (Ppp1r9b) nucleoplasm (Ppp1r9b)
cytoplasm (Ppp1r9b) signal transducer activity (Oprm1) signal transduction (Oprm1)
Anatomy Link Frequency
spine 2
Oprm1 (Mus musculus)
Ppp1r9b (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 151 100.00 Very High Very High Very High
MU agonist 23 99.20 Very High Very High Very High
Morphine 41 94.16 High High
Opioid 21 69.32 Quite High
mu opioid receptor 18 32.56 Quite Low
addiction 14 5.00 Very Low Very Low Very Low
dopamine receptor 6 5.00 Very Low Very Low Very Low
analgesia 4 5.00 Very Low Very Low Very Low
Dopamine 3 5.00 Very Low Very Low Very Low
narcan 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Opiate Addiction 10 5.00 Very Low Very Low Very Low
Pheochromocytoma 10 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 6 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Helminth Infection 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Frailty 1 5.00 Very Low Very Low Very Low
Cognitive Disorder 1 5.00 Very Low Very Low Very Low
Depression 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In mice, for example, opioid agonist activation of MOR causes a significant increase in the association of MOR with spinophilin, a dendritic spine-enriched scaffold protein [38].
Positive_regulation (increase) of MOR Binding (association) of spinophilin in spine associated with mu agonist and opioid receptor
1) Confidence 0.02 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2841195 Disease Relevance 0 Pain Relevance 0.77

General Comments

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