INT302134

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.28
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (TP53, CDKN1A) nucleus (TP53, CDKN1A) cytoplasm (TP53, CDKN1A)
cytosol (TP53, CDKN1A) cell differentiation (TP53) mitochondrion (TP53)
TP53 (Homo sapiens)
CDKN1A (Homo sapiens)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 52 52.96 Quite High
antagonist 5 46.12 Quite Low
Inflammation 26 5.00 Very Low Very Low Very Low
cINOD 17 5.00 Very Low Very Low Very Low
cytokine 11 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 126 100.00 Very High Very High Very High
Retinoblastoma 2 96.96 Very High Very High Very High
Death 27 50.00 Quite Low
Colon Cancer 23 21.32 Low Low
Apoptosis 151 5.00 Very Low Very Low Very Low
Fever 41 5.00 Very Low Very Low Very Low
INFLAMMATION 28 5.00 Very Low Very Low Very Low
Leukemia 9 5.00 Very Low Very Low Very Low
Prostate Cancer 8 5.00 Very Low Very Low Very Low
Lung Cancer 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, after DNA damage, p53, a tumor suppressor gene, activates transcription of p21, which inhibits cyclin E phosphorylation leading to hypophosphorylation of retinoblastoma protein (pRb) [81].
p53 Positive_regulation (activates) of Transcription (transcription) of p21 associated with cancer and retinoblastoma
1) Confidence 0.04 Published 2010 Journal International Journal of Cell Biology Section Body Doc Link PMC2841246 Disease Relevance 0.28 Pain Relevance 0.03

General Comments

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