INT302138

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Context Info
Confidence 0.06
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 2.08
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (BAK1) mitochondrion (BAK1) aging (BAK1)
endoplasmic reticulum (BAK1) intracellular (BAK1) plasma membrane (PTGER2)
PTGER2 (Homo sapiens)
BAK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 5 66.92 Quite High
COX-2 inhibitor 52 5.00 Very Low Very Low Very Low
Inflammation 26 5.00 Very Low Very Low Very Low
cINOD 17 5.00 Very Low Very Low Very Low
cytokine 11 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 151 100.00 Very High Very High Very High
Fever 41 100.00 Very High Very High Very High
Adenocarcinoma 5 99.08 Very High Very High Very High
Colon Cancer 23 98.48 Very High Very High Very High
Death 27 96.20 Very High Very High Very High
Cancer 126 90.92 High High
Familial Adenomatous Polyposis 4 88.52 High High
Lymphatic System Cancer 4 78.60 Quite High
Leukemia 9 78.12 Quite High
Hematologic Neoplasms 2 77.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been demonstrated that PGE2 can upregulate the level of the anti-apoptotic protein Bcl-2 in HCA-7 cells (adenocarcinoma), which produce significant amounts of PGE2.
PGE2 Positive_regulation (upregulate) of Gene_expression (level) of anti-apoptotic protein associated with adenocarcinoma, apoptosis and fever
1) Confidence 0.06 Published 2010 Journal International Journal of Cell Biology Section Body Doc Link PMC2841246 Disease Relevance 2.08 Pain Relevance 0.06

General Comments

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