INT302166

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.49
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transducer activity (PTGER2, EGFR) plasma membrane (PTGER2, EGFR) endosome (EGFR)
cell morphogenesis (EGFR) Golgi apparatus (EGFR) endoplasmic reticulum (EGFR)
PTGER2 (Homo sapiens)
EGFR (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 5 84.04 Quite High
COX-2 inhibitor 52 5.00 Very Low Very Low Very Low
Inflammation 26 5.00 Very Low Very Low Very Low
cINOD 17 5.00 Very Low Very Low Very Low
cytokine 11 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fever 41 100.00 Very High Very High Very High
Apoptosis 151 84.80 Quite High
Colon Cancer 23 76.60 Quite High
Cancer 126 73.48 Quite High
Adenocarcinoma 5 62.92 Quite High
Death 27 55.28 Quite High
Lung Cancer 7 50.72 Quite High
Familial Adenomatous Polyposis 4 47.60 Quite Low
Lymphatic System Cancer 4 37.68 Quite Low
Leukemia 9 37.20 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The transactivation of EGFR by PGE2 can lead also to AKT activation, which is a well-known survival pathway [49].
Positive_regulation (activation) of PGE2 Positive_regulation (transactivation) of EGFR associated with fever
1) Confidence 0.07 Published 2010 Journal International Journal of Cell Biology Section Body Doc Link PMC2841246 Disease Relevance 1.49 Pain Relevance 0.04

General Comments

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