INT302181

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Chuk) nucleus (Chuk) kinase activity (Chuk)
cytoplasm (Chuk)
Chuk (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 26 99.24 Very High Very High Very High
cytokine 11 94.64 High High
COX-2 inhibitor 52 60.52 Quite High
cINOD 17 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 28 99.24 Very High Very High Very High
Apoptosis 151 91.80 High High
Lung Cancer 7 72.32 Quite High
Cancer 126 62.00 Quite High
Death 27 50.00 Quite Low
Toxicity 2 43.80 Quite Low
Prostate Cancer 8 43.12 Quite Low
Colon Cancer 23 33.28 Quite Low
Metastasis 5 16.60 Low Low
Fever 41 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This group clearly demonstrates that antitumor and anti-inflammatory activities assigned to butein may be mediated in part through the direct inhibition of IKK, leading to the suppression of the NF?
Positive_regulation (mediated) of Negative_regulation (inhibition) of IKK associated with inflammation
1) Confidence 0.04 Published 2010 Journal International Journal of Cell Biology Section Body Doc Link PMC2841246 Disease Relevance 0.54 Pain Relevance 0.16

General Comments

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