INT302239

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.18
Pain Relevance 0.23

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
PC-3 2
BTG2 (Homo sapiens)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 52 86.36 High High
Endocannabinoid 18 84.56 Quite High
Inflammation 26 74.56 Quite High
antagonist 6 44.16 Quite Low
Cannabinoid 9 36.00 Quite Low
cINOD 17 5.00 Very Low Very Low Very Low
cytokine 15 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Prostate Cancer 59 100.00 Very High Very High Very High
Cervical Cancer 2 100.00 Very High Very High Very High
Apoptosis 158 89.40 High High
Skin Cancer 5 83.08 Quite High
Fever 41 75.04 Quite High
INFLAMMATION 28 74.56 Quite High
Colon Cancer 24 65.28 Quite High
Hepatocellular Cancer 4 61.76 Quite High
Disease 32 61.00 Quite High
Head & Neck Cancer 2 59.36 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Other studies have shown that the radiosensitivity of PC3 (human prostate carcinoma cells) and Hela (human cervical carcinoma cells) was enhanced after silencing of COX-2 by siRNA.
Positive_regulation (enhanced) of Gene_expression (radiosensitivity) of PC3 associated with cervical cancer and prostate cancer
1) Confidence 0.12 Published 2010 Journal International Journal of Cell Biology Section Body Doc Link PMC2841246 Disease Relevance 0.83 Pain Relevance 0.15
However, transfection of PC-3 cells with FAAH does increase their rate of 2-AG hydrolysis in addition to the effects on AEA hydrolysis [12].
Positive_regulation (transfection) of Gene_expression (transfection) of PC-3 in PC-3
2) Confidence 0.11 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2924377 Disease Relevance 0.35 Pain Relevance 0.08

General Comments

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