INT302271

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CDK4) nucleoplasm (CDK4) signal transduction (CDK4)
nucleolus (CDK4) nucleus (CDK4) cell cycle (CDK4)
CDK4 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 5 18.04 Low Low
COX-2 inhibitor 52 5.00 Very Low Very Low Very Low
Inflammation 26 5.00 Very Low Very Low Very Low
cINOD 17 5.00 Very Low Very Low Very Low
cytokine 11 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 151 83.28 Quite High
Fever 41 74.16 Quite High
Sarcoma 1 69.60 Quite High
Lung Cancer 7 66.96 Quite High
Cancer 126 60.72 Quite High
Death 27 50.00 Quite Low
Adenocarcinoma 5 48.40 Quite Low
Colon Cancer 23 10.60 Low Low
Metastasis 5 10.32 Low Low
INFLAMMATION 28 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
If phosphorylation occurs on T157 and T198 by PI3K (phosphoinositide 3-kinase), it triggers cell cycle transition by stabilizing the cyclin D1/cdk4 complex [55].
Positive_regulation (stabilizing) of cdk4
1) Confidence 0.09 Published 2010 Journal International Journal of Cell Biology Section Body Doc Link PMC2841246 Disease Relevance 0.84 Pain Relevance 0

General Comments

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