INT302288

Context Info Confidence 0.03 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.16 Pain Relevance 0.10

cell differentiation (Twist1) plasma membrane (PTGER2) nucleus (Twist1) DNA binding (Twist1) transcription factor binding (Twist1) signal transducer activity (PTGER2)

Twist1 (Mus musculus) PTGER2 (Homo sapiens)

Pain Link Frequency Relevance Heat COX-2 inhibitor 52 80.20 metalloproteinase 1 51.88 Inflammation 26 40.72 cINOD 17 5.00 cytokine 11 5.00 antagonist 5 5.00 aspirin 4 5.00 Paracetamol 3 5.00 Spinal cord 2 5.00 withdrawal 2 5.00

Disease Link Frequency Relevance Heat Fever 41 100.00 Cancer 126 96.40 Carcinoma 4 92.48 Apoptosis 151 84.44 Photosensitivity Disorders 1 79.40 Transitional Cell Carcinoma 1 56.88 Death 27 50.00 INFLAMMATION 28 40.72 Recurrence 1 39.48 Hypoxia 2 28.56

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

When RIF cells were transplanted in CH3/HeJ mice, for in vivo studies, PDT similarly induced an increase of COX-2 and PGE2.

PDT Positive_regulation (increase) of PGE2 associated with fever

1) Confidence 0.03 Published 2010 Journal International Journal of Cell Biology Section Body Doc Link PMC2841246 Disease Relevance 1.16 Pain Relevance 0.10

General Comments

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