INT302291

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.30
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (EGFR, Myc) cytoplasm (EGFR, Myc) nucleoplasm (Myc)
DNA binding (Myc) pigmentation (Myc) extracellular space (EGFR)
EGFR (Homo sapiens)
Myc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 5 72.64 Quite High
COX-2 inhibitor 52 9.20 Low Low
Inflammation 26 5.00 Very Low Very Low Very Low
cINOD 17 5.00 Very Low Very Low Very Low
cytokine 11 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
Paracetamol 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fever 41 99.44 Very High Very High Very High
Cancer 126 97.28 Very High Very High Very High
Adenocarcinoma 5 91.88 High High
Metastasis 5 90.16 High High
Lung Cancer 7 82.48 Quite High
Granuloma 1 59.68 Quite High
Death 27 50.00 Quite Low
Apoptosis 151 47.60 Quite Low
Sarcoma 1 33.92 Quite Low
INFLAMMATION 28 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
EGFR activation leads to activation of MAPK pathway that regulates cell proliferation by transactivating several oncogenes such as c-myc [60].
Positive_regulation (activation) of EGFR Positive_regulation (transactivating) of c-myc
1) Confidence 0.18 Published 2010 Journal International Journal of Cell Biology Section Body Doc Link PMC2841246 Disease Relevance 1.30 Pain Relevance 0.04

General Comments

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