INT302426

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.73
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.37
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (Rtn4r) plasma membrane (Rtn4r)
Anatomy Link Frequency
nucleus 1
Rtn4r (Rattus norvegicus)
Pain Link Frequency Relevance Heat
amygdala 12 50.88 Quite High
corticosteroid 196 50.00 Quite Low
Hippocampus 36 45.00 Quite Low
antagonist 16 11.68 Low Low
long-term potentiation 22 5.00 Very Low Very Low Very Low
depression 22 5.00 Very Low Very Low Very Low
nMDA receptor 20 5.00 Very Low Very Low Very Low
Calcium channel 16 5.00 Very Low Very Low Very Low
monoamine 10 5.00 Very Low Very Low Very Low
Neurotransmitter 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 10 94.00 High High
Repression 2 66.32 Quite High
Stress 88 65.28 Quite High
Dementia 2 18.80 Low Low
Cognitive Disorder 20 17.20 Low Low
Neurodegenerative Disease 6 15.04 Low Low
Depression 22 5.00 Very Low Very Low Very Low
Anxiety Disorder 14 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Bordatella Infection 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Like other nuclear receptors, nMR and nGR are organized according to canonical modules, including a ligand binding domain (LBD), a DNA binding domain (DBD), and two activation functions (AF-1 and AF-2) at their N- and C-terminals, respectively.
Localization (organized) of nGR
1) Confidence 0.73 Published 2010 Journal Mol Brain Section Body Doc Link PMC2841592 Disease Relevance 0.21 Pain Relevance 0
Whereas the unliganded nMR is primarily localized in the nucleus, the unoccupied nGR resides in the cytoplasm and only translocates to the nucleus upon ligand activation.
Localization (translocates) of nGR in nucleus
2) Confidence 0.73 Published 2010 Journal Mol Brain Section Body Doc Link PMC2841592 Disease Relevance 0.15 Pain Relevance 0.03

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox