INT302436

Context Info Confidence 0.01 First Reported 2010 Last Reported 2010 Negated 1 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.07 Pain Relevance 0.19

endosome (Prf1) extracellular region (Prf1) cytoplasmic membrane-bounded vesicle (Prf1) plasma membrane (Prf1) transmembrane transport (Prf1)

Anatomy Link Frequency pore 2 Prf1 (Mus musculus)

Pain Link Frequency Relevance Heat nMDA receptor 10 77.24 long-term potentiation 11 70.32 Calcium channel 8 61.68 corticosteroid 98 53.12 dexamethasone 3 43.24 agonist 3 15.56 Hippocampus 18 5.00 depression 11 5.00 antagonist 8 5.00 amygdala 6 5.00

Disease Link Frequency Relevance Heat Sprains And Strains 2 73.84 Stress 44 5.00 Depression 11 5.00 Cognitive Disorder 10 5.00 Anxiety Disorder 7 5.00 Shock 5 5.00 Neurodegenerative Disease 3 5.00 Apoptosis 3 5.00 Bordatella Infection 2 5.00 Targeted Disruption 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

On the other hand, Chameau et al. [105] found by quantitative PCR that corticosterone did not change the mRNA expression of the pore-forming Cav1 subunit of the L-type Ca2+ channel, and ruled out transcriptional mechanisms in the effects they observed.

Neg (not) Positive_regulation (change) of Transcription (expression) of pore-forming Cav1 subunit in pore

1) Confidence 0.01 Published 2010 Journal Mol Brain Section Body Doc Link PMC2841592 Disease Relevance 0.07 Pain Relevance 0.19

General Comments

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