INT302469

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.82
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (F2, MMP9) extracellular space (F2, MMP9) extracellular region (F2, MMP9)
proteinaceous extracellular matrix (MMP9) plasma membrane (F2) extracellular matrix organization (MMP9)
F2 (Homo sapiens)
MMP9 (Homo sapiens)
Pain Link Frequency Relevance Heat
cva 28 100.00 Very High Very High Very High
cytokine 22 95.84 Very High Very High Very High
Inflammation 40 95.44 Very High Very High Very High
metalloproteinase 24 94.48 High High
ischemia 2 56.68 Quite High
depression 4 14.80 Low Low
withdrawal 8 5.00 Very Low Very Low Very Low
Dismenorea 8 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hemorrhage 28 100.00 Very High Very High Very High
INFLAMMATION 46 95.44 Very High Very High Very High
Infection 100 89.40 High High
Premature Birth 282 89.04 High High
Abruptio Placentae 8 80.00 Quite High
Genetic Predisposition To Disease 2 79.36 Quite High
Recurrence 2 63.60 Quite High
Rupture 32 60.72 Quite High
Cv Unclassified Under Development 2 56.68 Quite High
Thrombosis 8 52.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In vitro, thrombin significantly increases MMP-1, MMP-3, and MMP-9 protein expression in decidual cells and fetal membranes collected from uncomplicated term pregnancies [47-49].
thrombin Positive_regulation (increases) of Gene_expression (expression) of MMP-9
1) Confidence 0.01 Published 2010 Journal BMC Pregnancy Childbirth Section Body Doc Link PMC2841774 Disease Relevance 0.72 Pain Relevance 0.26
Thrombin, generated as a result of choriodecidual hemorrhage, also increases MMP-9 production in amniochorion cultures [49].
Thrombin Positive_regulation (increases) of Gene_expression (production) of MMP-9 associated with cva
2) Confidence 0.01 Published 2010 Journal BMC Pregnancy Childbirth Section Body Doc Link PMC2841774 Disease Relevance 1.10 Pain Relevance 0.35

General Comments

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