INT302620

Context Info Confidence 0.41 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

intracellular (Rac1) enzyme binding (Rac1) GTPase activity (Rac1) cytoplasm (Rac1) cell proliferation (Rac1) cell motility (Rac1)

Rac1 (Mus musculus)

Pain Link Frequency Relevance Heat ischemia 2 5.00 cINOD 1 5.00 antagonist 1 5.00

Disease Link Frequency Relevance Heat Cancer 85 50.00 Targeted Disruption 6 5.00 Colorectal Cancer 4 5.00 Cv Unclassified Under Development 4 5.00 Metastasis 3 5.00 Pathologic Neovascularization 3 5.00 Adhesions 2 5.00 Injury 2 5.00 Hemangiosarcoma 2 5.00 Skin Cancer 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

3-null mice reduced significantly Rac1 mRNA levels (Figure 7A), total protein levels (Figure 7B), and active Rac1 levels (Figure 1A).

Negative_regulation (reduced) of Transcription (levels) of Rac1

1) Confidence 0.41 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2842301 Disease Relevance 0 Pain Relevance 0

General Comments

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