INT302688

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.68
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.30
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (OPA1) mitochondrion organization (OPA1) GTPase activity (OPA1)
OPA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Multiple sclerosis 20 5.00 Very Low Very Low Very Low
peripheral neuropathy 16 5.00 Very Low Very Low Very Low
Migraine 8 5.00 Very Low Very Low Very Low
headache 6 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
adenocard 2 5.00 Very Low Very Low Very Low
Electroencephalography 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 6 90.24 High High
Syndrome 12 89.28 High High
Disease 40 70.56 Quite High
Neurological Disease 4 50.00 Quite Low
Congenital Anomalies 8 47.16 Quite Low
Optic Atrophy 30 39.08 Quite Low
Demyelinating Disease 24 5.00 Very Low Very Low Very Low
Chronic Progressive External Ophthalmoplegia 22 5.00 Very Low Very Low Very Low
Ataxia 22 5.00 Very Low Very Low Very Low
Deafness 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
40% of total OPA1 mRNA transcripts, this could explain the relatively mild pathogenic nature of exon 5b variants on their own.
Transcription (transcripts) of OPA1
1) Confidence 0.68 Published 2010 Journal Brain Section Body Doc Link PMC2842512 Disease Relevance 0.21 Pain Relevance 0
We identified 9 novel OPA1 variants which were not found in 150–300 age- and ethnically-matched control subjects: (i) c.344C > T (p.A115V) in exon 2; (ii) c.768C > G (p.S256R) in exon 5b; (iii) c.728T > A (p.L243X) in exon 7; (iv) c.854A > G (p.Q285R) in exon 8; (v) c.1071A > G (p.A358A) in exon 11; (vi) c.1327G > A (p.A443T) in exon 14; (vii) c.1462G > A (p.G488R) in exon 15; (viii) c.1484C > T (p.A495V) in exon 15; and (ix) c.1642G > A (p.V548I) in exon 17 (Supplementary Fig. 1).
Transcription (found) of OPA1
2) Confidence 0.46 Published 2010 Journal Brain Section Body Doc Link PMC2842512 Disease Relevance 0.09 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox