INT302734

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Context Info
Confidence 0.41
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.58
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ghrl) extracellular region (Ghrl) cytoplasm (Ghrl)
Anatomy Link Frequency
plasma 2
sympathetic nervous system 2
Ghrl (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Somatostatin 7 72.80 Quite High
tolerance 10 26.40 Quite Low
transdermal 2 17.36 Low Low
antagonist 19 5.00 Very Low Very Low Very Low
agonist 17 5.00 Very Low Very Low Very Low
Inflammation 10 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
medulla 4 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
vagus nerve 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sleep Disorders 7 98.42 Very High Very High Very High
Hypoglycemia 4 94.76 High High
Body Weight 20 94.64 High High
Diabetes Mellitus 8 89.84 High High
Impaired Glucose Tolerance 15 89.36 High High
Appetite Loss 13 88.16 High High
Obesity 17 77.60 Quite High
Metabolic Syndrome 3 65.44 Quite High
Hypertension 1 63.64 Quite High
Acute Erythroblastic Leukemia 2 8.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sleep deprivation also leads to changes in the activation of the sympathetic nervous system, to reduced levels of leptin and to increased levels of ghrelin in the general circulation [13].
Negative_regulation (reduced) of Positive_regulation (increased) of ghrelin in sympathetic nervous system associated with sleep disorders
1) Confidence 0.41 Published 2010 Journal International Journal of Endocrinology Section Body Doc Link PMC2842885 Disease Relevance 0.81 Pain Relevance 0
In mice, plasma bioactive decanoylated ghrelin increases and octanoylated ghrelin paradoxically decreases during fasting [90], suggesting precise posttranslational control [72].
Negative_regulation (decreases) of Positive_regulation (increases) of ghrelin in plasma
2) Confidence 0.20 Published 2010 Journal International Journal of Peptides Section Body Doc Link PMC2925380 Disease Relevance 0.77 Pain Relevance 0.04

General Comments

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