INT302783

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Context Info
Confidence 0.29
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.42
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (S1pr1) plasma membrane (S1pr1) signal transducer activity (S1pr1)
S1pr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 64 73.04 Quite High
Inflammation 43 72.64 Quite High
rheumatoid arthritis 65 49.60 Quite Low
metalloproteinase 1 27.72 Quite Low
chemokine 2 23.08 Low Low
cytokine 15 22.60 Low Low
methotrexate 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 45 100.00 Very High Very High Very High
Arthritis 62 73.04 Quite High
Necrosis 5 64.64 Quite High
Cancer 12 64.28 Quite High
INFLAMMATION 17 50.52 Quite High
Rheumatoid Arthritis 65 49.60 Quite Low
Adhesions 1 23.48 Low Low
Disease 3 10.92 Low Low
Death 3 5.00 Very Low Very Low Very Low
Juvenile Chronic Polyarthritis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Additionally, it was shown that the secreted form of S1P also regulated cell survival and apoptosis by its capacity to bind to and activate 5 specific G protein-coupled receptors, S1P1-S1P15 [35].
Positive_regulation (activate) of Localization (secreted) of S1P associated with apoptosis
1) Confidence 0.29 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2842969 Disease Relevance 0.42 Pain Relevance 0.10

General Comments

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