INT302833

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Context Info
Confidence 0.03
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.00
Pain Relevance 0.57

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mmp3) extracellular space (Mmp3) extracellular region (Mmp3)
proteinaceous extracellular matrix (Mmp3) nucleus (Mmp3) protein complex (Mmp3)
Mir155 (Mus musculus)
Mmp3 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 65 99.84 Very High Very High Very High
Osteoarthritis 1 97.76 Very High Very High Very High
cytokine 15 83.20 Quite High
Arthritis 64 66.24 Quite High
Inflammation 43 65.84 Quite High
Inflammatory response 3 11.44 Low Low
methotrexate 4 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 65 99.84 Very High Very High Very High
Osteoarthritis 1 97.76 Very High Very High Very High
Arthritis 62 66.24 Quite High
Repression 1 40.16 Quite Low
INFLAMMATION 17 11.08 Low Low
Apoptosis 45 5.00 Very Low Very Low Very Low
Cancer 12 5.00 Very Low Very Low Very Low
Necrosis 5 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Juvenile Chronic Polyarthritis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, Stanczyk et al. [111] showed that forced expression of miR-155 repressed the levels of MMP-3 (stromelysin-1) produced by RA-SF. miR-155 also reduced the expression of MMP-1 (collagenase-1) and MMP-3 induced by TLR ligands, TNF-?
Gene_expression (expression) of miR-155 Negative_regulation (repressed) of Gene_expression (produced) of stromelysin-1 associated with rheumatoid arthritis
1) Confidence 0.03 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2842969 Disease Relevance 1.00 Pain Relevance 0.57

General Comments

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