INT302837

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Context Info
Confidence 0.01
First Reported 2009
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.98
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Trp53) mitochondrion (Trp53) endoplasmic reticulum (Trp53)
enzyme binding (Trp53) protein complex assembly (Trp53) DNA binding (Trp53)
TNFRSF10D (Homo sapiens)
Trp53 (Mus musculus)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 65 91.92 High High
agonist 2 75.88 Quite High
Arthritis 64 57.36 Quite High
Inflammation 43 50.00 Quite Low
cytokine 15 5.00 Very Low Very Low Very Low
methotrexate 4 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Osteoarthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 45 96.12 Very High Very High Very High
Rheumatoid Arthritis 65 91.92 High High
Arthritis 62 57.36 Quite High
Experimental Arthritis 1 45.68 Quite Low
Medulloblastoma 1 29.32 Quite Low
Cancer 12 13.88 Low Low
INFLAMMATION 17 5.00 Very Low Very Low Very Low
Necrosis 5 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Juvenile Chronic Polyarthritis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Of note, decoy receptor-2 (DcR2) a TRAIL-R and a target for p53 siRNA [131], but only in combination with Ad5hTRAIL, eliminated the TRAIL-induced resistance to apoptosis in these cells to a more significant extent than when the cells were transfected with Ad5hTRAIL alone.
DcR2 Binding (target) of p53 associated with apoptosis
1) Confidence 0.01 Published 2009 Journal Mediators of Inflammation Section Body Doc Link PMC2842969 Disease Relevance 0.98 Pain Relevance 0.28

General Comments

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