INT302877

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Context Info
Confidence 0.19
First Reported 2010
Last Reported 2010
Negated 1
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.08
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ccl2) aging (Ccl2) extracellular region (Ccl2)
cytoskeleton organization (Ccl2) cytoplasm (Ccl2)
Anatomy Link Frequency
microglia 2
Ccl2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
chemokine 14 100.00 Very High Very High Very High
cva 46 99.68 Very High Very High Very High
Inflammation 20 78.72 Quite High
cytokine 11 46.12 Quite Low
antagonist 6 45.28 Quite Low
Inflammatory response 11 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
adenocard 4 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pulmonary Embolism 45 99.68 Very High Very High Very High
Status Epilepticus 106 84.08 Quite High
INFLAMMATION 25 78.72 Quite High
Injury 4 47.60 Quite Low
Toxicity 1 40.16 Quite Low
Death 7 36.32 Quite Low
Sprains And Strains 13 7.16 Low Low
Urological Neuroanatomy 20 5.00 Very Low Very Low Very Low
Hypertension 13 5.00 Very Low Very Low Very Low
Convulsion 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Measured levels of the chemokines MCP-1, CINC-1, CINC-2, and CINC-3 are shown in Table 1 and were not significantly different in the PE versus sham animals at either time point.


Neg (not) Regulation (different) of Localization (levels) of MCP-1 associated with chemokine and cva
1) Confidence 0.19 Published 2010 Journal Thromb J Section Body Doc Link PMC2843658 Disease Relevance 0.79 Pain Relevance 0.45
Taken together, our findings indicate that P2X7 receptor may regulate MCP-1 expression/release in microglia, which may modulate MIP-2 expression/release in neurons and astrocytes via CCR2.
Spec (may) Regulation (regulate) of Localization (release) of MCP-1 in microglia
2) Confidence 0.18 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2964655 Disease Relevance 0.29 Pain Relevance 0.04

General Comments

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