INT302908

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.22
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Agt) signal transduction (Agtr2) plasma membrane (Agtr2)
extracellular matrix organization (Agt) transcription factor binding (Agtr2) signal transducer activity (Agtr2)
Anatomy Link Frequency
heart 2
Agtr2 (Mus musculus)
Agt (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 1 68.56 Quite High
medulla 3 34.56 Quite Low
agonist 1 18.16 Low Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
vagus nerve 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
dorsal root ganglion 1 5.00 Very Low Very Low Very Low
Peripheral nervous system 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Heart Rate Under Development 3 85.60 High High
Cv Unclassified Under Development 6 55.76 Quite High
Nervous System Malformation 10 50.00 Quite Low
Pressure And Volume Under Development 3 41.36 Quite Low
Pressure Volume 2 Under Development 3 23.68 Low Low
Neuroblastoma 13 5.00 Very Low Very Low Very Low
Congenital Anomalies 8 5.00 Very Low Very Low Very Low
Ganglion Cysts 5 5.00 Very Low Very Low Very Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to a reduced ability to increase or decrease heart rate appropriately in response to nitroprusside and angiotensin II, respectively, the Nav2 hypomorphic mutant mice showed a much longer duration of pressure change after both angiotensin and nitroprusside treatment that was most likely due to the blunted heart rate response (data not shown).
angiotensin II Positive_regulation (increase) of Gene_expression (duration) of angiotensin in heart
1) Confidence 0.00 Published 2010 Journal Neural Dev Section Body Doc Link PMC2843687 Disease Relevance 0.22 Pain Relevance 0.03

General Comments

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