INT302959

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Context Info
Confidence 0.10
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.24
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Jag2)
Jag2 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 6 85.40 High High
Inflammation 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 19 68.64 Quite High
Apoptosis 63 65.84 Quite High
Death 5 42.48 Quite Low
Necrosis 3 42.40 Quite Low
Toxicity 8 32.32 Quite Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Osteogenesis Imperfecta 4 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 2 5.00 Very Low Very Low Very Low
Hepatotoxicity 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Altogether, these data strongly suggest that nSMase2, which is mutated and deficient in fro/fro mice [19], is activated and required for the activation of the SM/Cer pathway elicited by TNF?
Positive_regulation (activated) of Positive_regulation (activation) of SM/Cer
1) Confidence 0.10 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2843740 Disease Relevance 0.24 Pain Relevance 0.04

General Comments

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