INT302978

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.10
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nqo1) oxidoreductase activity (Nqo1) cytoplasm (Nqo1)
Nqo1 (Mus musculus)
Smpd2 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 12 90.08 High High
Inflammation 8 83.36 Quite High
cytokine 6 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 126 97.36 Very High Very High Very High
Osteogenic Sarcomas 4 92.12 High High
INFLAMMATION 10 83.36 Quite High
Stress 38 81.60 Quite High
Toxicity 16 59.88 Quite High
Rhinitis 2 46.32 Quite Low
Injury 2 9.36 Low Low
Death 10 5.00 Very Low Very Low Very Low
Osteogenesis Imperfecta 8 5.00 Very Low Very Low Very Low
Necrosis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
and oxLDLs, two agents known to activate nSMase, via different signaling mechanisms.
oxLDLs Positive_regulation (activate) of nSMase
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2843740 Disease Relevance 0.90 Pain Relevance 0.07
These data show that nSMase activation by oxLDLs and TNF?
oxLDLs Positive_regulation (activation) of nSMase
2) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2843740 Disease Relevance 0.20 Pain Relevance 0.15

General Comments

This test has worked.

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